Detection and quantification of vancomycin in biological fluids

Details Detection and quantification of vancomycin in biological fluids Detection and quantification of vancomycin in biological fluids

G - Physics

01

N

G01N 33/58 (2006.01) C07K 16/14 (2006.01) G01N 33/531 (2006.01) G01N 33/533 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2346717

Immunoassay reagents, methods and test kits for the specific quantification of vancomycin in a test sample are disclosed. The reagent comprises antibodies prepared with immunogens of Figure 6 wherein P is an immunogenic carrier material and X is a linking moiety. Also described is the synthesis of labeled reagents of Figure 8 wherein Q is a detectable moiety, preferably fluorescein or a fluorescein derivative, and X is a linking moiety.

La présente invention concerne des immunoréactifs, des procédés et des kits d'essai permettant de procéder à une quantification spécifique de la vancomycine dans un échantillon d'essai. Le réactif comprend des anticorps préparés avec des immunogènes selon la formule de la figure 6, dans laquelle P est un matériau porteur immunogène et X une fraction de liaison. L'invention concerne également des réactifs marqués. Selon la formule de la figure 8, Q est une fraction détectable, fluorescéine ou dérivé de la fluorescéine de préférence, et X une fraction de liaison.

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