A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 41/00 (2006.01) A61K 31/409 (2006.01) A61K 47/42 (2006.01) A61K 49/00 (2006.01) A61N 5/06 (2006.01) A61P 9/00 (2006.01) C09B 47/00 (2006.01) G01N 21/64 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2449828
The present invention relates to methods for selectively targeting Photodynamic Therapy ("PDT") to inflammatory components of vulnerable plaques. As such, the present invention provides methods for the identification of vulnerable plaques, as well as methods to treat vulnerable plaques by selectively targeting and/or eliminating the inflammatory components of vulnerable plaques. The invention further relates to a specially designed intravascular device that delivers excitation light to the plaque surface inside the artery and receives emitted fluorescence light when a fluorescent signal is detected.
La présente invention concerne des méthodes permettant de cibler, de manière sélective, la thérapie photodynamique ("TPD") sur des composés inflammatoires de plaques vulnérables. A ce titre, cette invention concerne des méthodes d'identification de plaques vulnérables ainsi que des méthodes de traitement de plaques vulnérables par ciblage sélectif et/ou élimination sélective des composés inflammatoires de plaques vulnérables. Ladite invention concerne également un dispositif intravasculaire conçu spécialement à cet effet, lequel dispositif fournit une lumière d'excitation à la surface des plaques à l'intérieur de l'artère et reçoit une lumière de fluorescence, lorsqu'un signal fluorescent est détecté.
Anderson Rox
Fischman Alan
Hamblin Michael R.
Hasan Tayyaba
Muller James
Mbm Intellectual Property Law Llp
The General Hospital Corporation
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