G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01)
Patent
CA 2613187
The present invention relates to the field of therapeutic antibodies. The invention especially relates to a method of detecting the target antigen of a therapeutic antibody in a sample comprising the steps of a) providing the sample to be analyzed, b) incubating said sample with said therapeutic antibody under conditions appropriate for binding of said therapeutic antibody to said target antigen, whereby a target antigen-therapeutic antibody-complex is formed, and c) detecting the complex formed in (b).
La présente invention concerne les anticorps thérapeutiques. L'invention concerne en particulier une méthode de détection de l'antigène cible d'un anticorps thérapeutique dans un échantillon, consistant a) à obtenir l'échantillon à analyser, b) à incuber ledit échantillon avec l'anticorps thérapeutique dans des conditions adaptées pour la liaison de l'anticorps thérapeutique à l'antigène cible, un complexe antigène cible-anticorps thérapeutique étant ainsi formé, et c) à détecter le complexe formé au cours de l'étape (b).
Lenz Helmut
Scheuer Werner
Thier Martina
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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