Detection of basement membrane components as diagnostic of...

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G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01) G01N 33/576 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2005190

39 DETECTION OF BASEMENT MEMBRANE COMPONENTS AS DIAGNOSTIC OF CANCER AND OTHER DISEASES Abstract of the Disclosure Method for the diagnosis diseases that result in the release of fragments of basement membrane, including fragments, intact molecules and/or complexes of basement membrane components, are disclosed. Detection of basement membrane fragments, intact molecules and/or complexes in a biological fluid by the immunological and physicochemical methods of the present invention allows the diagnosis of a variety of diseases, including cancers, collagen degenera- tive diseases, and hepatitis. Suitable biological fluids include urine, serum, synovial fluid, and cerebrospinal fluid.

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