Detection of cancer markers

G - Physics – 01 – N

Patent

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Details

G01N 27/327 (2006.01) A61B 5/1473 (2006.01) G01N 27/416 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2685406

The present invention relates to combining surface molecular imprinting (SMI) with the production of self-assembled monolayers (SAM) of hydroxyl alkanethiolate molecules on gold coated chip surfaces. In this technique, the sensing element is placed on the transducer and the whole assembly can then be miniaturized and integrated into a smart chip. These sensors can detect, nanomolar quantities of complex biomolecules.

L'invention concerne la combinaison d'impression moléculaire de surface (SMI) à la production de monocouches auto-assemblées (SAM) de molécules d'alcanethiolate d'hydroxyle sur des surfaces de puce recouvertes d'or. Dans cette technique, l'élément de détection est placé sur le transducteur et l'assemblage entier peut alors être miniaturisé et intégré dans une puce intelligente. Ces capteurs peuvent détecter des quantités nanomolaires de biomolécules complexes.

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