Detection of carbohydrate biomarkers

Details Detection of carbohydrate biomarkers Detection of carbohydrate biomarkers

G - Physics

01

N

G01N 33/00 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2606721

The present invention generally relates to detection of carbohydrate biomarkers in nipple aspirate fluid samples. One aspect of the invention is a method for assaying a nipple aspirate fluid for the presence of TF or Tn carbohydrate biomarker. The assay generally employs an immobilized capture agent specific for TF or Tn and can be further coupled to either direct or indirect detection of bound TF or Tn carbohydrate biomarker through the use of a labeled binding agent.

L'invention concerne de manière générale la détection de marqueurs biologiques carbohydrates dans des échantillons de fluide d'aspiration du mamelon (NAF). Un aspect de l'invention concerne un procédé d'analyse d'un fluide d'aspiration du mamelon pour rechercher la présence d'un marqueur biologique carbohydrate TF ou Tn. Cette analyse consiste de manière générale à utiliser un agent de capture immobilisé spécifique de TF ou Tn et elle peut être accompagnée par ailleurs d'une détection directe ou indirecte d'un marqueur biologique carbohydrate TF ou Tn lié, à l'aide d'un agent liant marqué.

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