Detection of copy number changes in colon cancer

Details Detection of copy number changes in colon cancer Detection of copy number changes in colon cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2377664

The present invention provides methods of screening for colon carcinoma cells in a sample. The methods comprise providing a nucleic acid sample from a premalignant lesion in colorectal tissue from a human patient and contacting the sample with a nucleic acid probe that selectively hybridizes to a chromosomal region at 20q.

L'invention concerne des méthodes de criblage de cellules cancéreuses du colon dans un échantillon. Ces méthodes consistent à fournir un échantillon d'acide nucléique provenant d'une lésion précancéreuse du tissu colorectal d'un patient humain, et à mettre cet échantillon en contact avec une sonde d'acide nucléique qui s'hybride sélectivement avec une région chromosomale à 20q.

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