Detection of cox-2 activity and anandamide metabolites

Details Detection of cox-2 activity and anandamide metabolites Detection of cox-2 activity and anandamide metabolites

C - Chemistry, Metallurgy

07

K

C07K 16/40 (2006.01) A61K 31/5575 (2006.01) C12N 1/00 (2006.01) C12Q 1/26 (2006.01) C12Q 1/48 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) G01N 33/58 (2006.01) G01N 33/88 (2006.01)

Patent

CA 2422803

The present invention relates generally to cyclooxygenase enzymes (COX) and more particularly the COX-2 enzyme. The present invention provides compositions, methods and articles of manufacture (kits) for determining the COX-2 activity in a sample of a subject, such as a patient or a cell culture. The present invention is useful in monitoring inflammation and cancer, or other disease processes, in patients in a clinical setting.

La présente invention concerne généralement des enzymes de cyclooxygénase (COX) et notamment l'enzyme COX-2. Cette invention a trait à des compositions, des méthodes et des articles de fabrication (kits) servant à déterminer l'activité COX-2 dans un échantillon prélevé chez un sujet, par exemple un patient ou une culture cellulaire. Ladite invention est utile dans le cadre de la surveillance d'inflammations et de cancers, ou autres processus morbides, chez des patients en un milieu clinique.

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