Detection of endotoxin in pharmaceutical preparations by...

Details Detection of endotoxin in pharmaceutical preparations by... Detection of endotoxin in pharmaceutical preparations by...

C - Chemistry, Metallurgy

12

Q

150/19, 358/9, 1

C12Q 1/04 (2006.01) C12Q 1/10 (2006.01) G01N 30/02 (2006.01) G01N 30/84 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2032133

2032133 9013534 PCTABS00002 The present invention relates to a method of detection of endotoxin in polypeptide compositions. In particular, this invention contemplates a method for measuring endotoxin by quantitating the amount of a volatile derivatized component of endotoxin, beta-hydroxymyristic acid, present in polypeptide compositions. The present invention can be used for testing the endotoxin content of products which are intended for use in clinical medicine, including those produced by recombinant DNA technology.

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