C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 31/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2655546
The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative breast disease as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative breast disease as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative breast disease who is at risk of developing breast cancer. The invention also provides kits for performing the above methods.
La présente invention concerne un procédé permettant de déterminer in vitro qu'une tumeur résultant d'une pathologie mammaire proliférante est sensible à un traitement anti- AEstrogénique. L'invention concerne en outre un procédé permettant de déterminer in vitro qu'un patient candidat atteint d'une pathologie mammaire proliférante est apte à recevoir un traitement anti-AEstrogénique. Dans un autre aspect, l'invention concerne un procédé d'identification in vitro d'un individu atteint d'une pathologie mammaire proliférante non cancéreuse qui court le risque de développer un cancer du sein. L'invention concerne également des trousses destinées à la mise en AEuvre des procédés susmentionnés.
A-Kuraya Khawla
Holst Frederik
Ruiz Christian
Sauter Guido
Simon Ronald
Shapiro Cohen
Universitaetsklinikum Hamburg-Eppendorf
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