Detection of glucose in solutions also containing an...

G - Physics – 01 – N

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G01N 33/66 (2006.01) C07F 5/02 (2006.01)

Patent

CA 2433863

Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta- diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha- hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.

L'invention concerne des compositions et des procédés permettant de déterminer la présence ou la concentration de glucose dans un échantillon contenant également un acide alpha-hydroxy ou une béta-diketone. Ce procédé utilise un composé possédant au moins deux éléments de reconnaissance de glucose, orientés de sorte que l'interaction entre ledit composé et le glucose soit plus stable que l'interaction entre ce composé et l'acide alpha-hydroxy ou la béta-dikétone, et que la présence de l'acide alpha-hydroxy ou de la béta-dikétone n'interfère pas sensiblement sur ladite détermination.

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