Detection of hiv-related proteins in urine

Details Detection of hiv-related proteins in urine Detection of hiv-related proteins in urine

G - Physics

01

N

G01N 33/68 (2006.01) G01N 33/493 (2006.01)

Patent

CA 2738666

A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HFV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed.

La présente invention concerne une méthode de détection de l'infection par le VIH chez un mammifère. Ladite méthode comprend les étapes suivantes : isolation des exosomes dans un échantillon d'urine d'un mammifère ; et détection de la présence d'un biomarqueur spécifique au HIV dans lesdits exosomes isolés. L'invention porte en outre sur une méthode de diagnostic d'une maladie associée au VIH chez un mammifère, en particulier une néphropathie associée au VIH.

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