Detection of htlv antibodies utilizing recombinant proteins

C - Chemistry – Metallurgy – 12 – N

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C12N 15/49 (2006.01) C07K 14/15 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2223235

Assays utilizing HTLV-I and HTLV-II recombinant antigens to detect antibody to HTLV in a test sample. Antigens utilized include HTLV-I gp46, HTLV-I gp21, HTLV-I p24, HTLV-II gp21 and HTLV-II p24 and any combination thereof. Test kits which include these HTLV-I and HTLV-II antigens, as well as the plasmids from which these recombinant antigens were produced, also are provided.

L'invention porte sur des techniques recourant à des antigènes de recombinaison de l'HTLV-I et de l'HTLV-II pour détecter les anticorps du HTVL dans un échantillon test. Les antigènes utilisés comprennent les HTLV-Igp46, HTLV-Igp21, HTLV-Ip24, HTLV-IIgp21 et HTLV-IIgp24 ou l'une de leurs combinaisons. L'invention porte également sur les trousses qui comprennent les antigènes de l'HTLV-I et de l'HTLV-II, et les plasmides à partir desquels ces antigènes de recombinaison ont été produits.

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