Detection of human cysteine-rich secretory protein (crisp1)...

Details Detection of human cysteine-rich secretory protein (crisp1)... Detection of human cysteine-rich secretory protein (crisp1)...

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2693546

The invention relates to the detection of human cysteine-rich secretory protein (CRISP1) as a marker for the presence or absence of epididymal secretions in an ejaculate. Described herein are methods for assessing the presence of epididymal secretions in human semen, methods for evaluating successfulness of vasectomy in men, methods for evaluating successfulness of vasovasostomy in men, and methods for discriminating between obstructive and non-obstructive azoospermia in men. Generally, the methods comprise detecting in the semen sample presence or absence of CRISP1. Also described are kits useful for diagnostic applications in humans according to the described evaluation methods.

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