Detection of human papilloma virus (hpv) utilizing invasive...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/70 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2539703

The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.

La présente invention concerne des compositions et des techniques de détection et de caractérisation de séquences de papillomavirus. La présente invention concerne plus particulièrement des compositions, des techniques et des kits destinés à des dosages de structure de clivage invasives (par exemple le dosages INVADER) afin d'analyser des échantillons d'acides nucléiques, par exemple, de patients en vue de détecter la présence d'une séquence quelconque dans une collection de séquences de papillomavirus. Cette invention concerne aussi des compositions, des techniques et des kits permettant d'analyser des ensembles de séquences de papillomavirus dans une cuve de réaction unique.

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