Detection of influenza virus

Details Detection of influenza virus Detection of influenza virus

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) C07K 14/435 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) C07K 14/11 (2006.01)

Patent

CA 2676555

The present application describes methods for detecting influenza A and/or influenza B and/or distinguishing between pathogenic and seasonal influenza A subtypes. Many of these preferred formats employ pan-specific antibodies (i.e., that react with all or at least multiple strains within an influenza type) to detect presence of influenza A and/or influenza B and PDZ domains in combination with panspecific antibodies to influenza A to distinguish pathogenic and seasonal influenza A subtypes.

Cette invention se rapporte à des procédés permettant de détecter l'influenzavirus de type A et/ou l'influenzavirus de type B et/ou de faire la distinction entre les sous-types pathogènes et saisonniers de l'influenzavirus A. Bon nombre de ces formats préférés utilisent des anticorps Pan-spécifiques (c'est-à-dire qui réagissent avec toutes les souches ou au moins plusieurs souches d'un type de grippe) pour détecter la présence de la grippe A et/ou de la grippe B et des domaines PDZ en association avec des anticorps Pan-spécifiques dirigés contre la grippe A pour faire la distinction entre les sous-types pathogènes et saisonniers de la grippe A.

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