Detection of lead in blood

G - Physics – 01 – N

Patent

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Details

G01N 27/42 (2006.01) G01N 33/487 (2006.01) G01N 33/49 (2006.01) G01N 27/49 (2006.01) G01N 33/18 (2006.01)

Patent

CA 2183074

A device (10) is disclosed for measuring the concentration of metal ions in solution, particularly lead in blood. The device comprises a mercury free electrode (16), which is separated from the test solution (21) by a layer of material (20) which permits passage therethrough of the ions to be measured. In preferred embodiments an insulating layer (18) having an array of photoablated holes (19) is disposed between the electrode and the ion-permeable layer (20). Also disclosed are methods for operating the device ion measuring ion concentration using anodic stripping voltametry, and assay kits incorporating devices as described together with appropriate meters and circuitry.

Le dispositif décrit (10) sert à mesurer la concentration d'ions de métal en solution, en particulier de plomb dans le sang. Ce dispositif comprend une électrode sans mercure (16), qui est séparée de la solution à tester (21) par une couche d'un matériau (20), laquelle permet le passage à travers elle des ions à mesurer. Dans des modes de réalisation préférés, une couche isolante (18), présentant un réseau de trous (19) produits par photoablation, est disposée entre l'électrode et la couche (20) perméable aux ions. Cette invention concerne également des procédés pour utiliser un tel dispositif et pour mesurer la concentration d'ions par dosage voltmétrique à épuisement anodique, ainsi que des kits de dosage dans lesquels sont incorporés ces dispositifs avec les éléments de mesure et les circuits appropriés.

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