Detection of malignant tumor cells

C - Chemistry – Metallurgy – 12 – N

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167/45, 195/1.10

C12N 5/02 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12P 1/00 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1215919

DETECTION OF MALIGNANT TUMOR CELLS ABSTRACT OF THE DISCLOSURE Described herein is the production of two products which are distinct species of anti-malignin antibody, and the production of three artificially produced species of cell each of which has the distinguishing characteristic of manufacturing either one or both species of anti-malignin antibody. These anti-malignin products are useful to detect the presence of cancerous or malig- nant tumor cells. These anti-malignin products attach preferentially to cancerous or malignant tumor cells in cell collections in vitro or in vivo and thus can be detected by any attached visible or other signal emitter. This preferential attachment to malignant tumor cells also makes these products, useful for metabolic and therapeutic purposes.

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