Detection of mammary tumor virus-like sequences in human...

Details Detection of mammary tumor virus-like sequences in human... Detection of mammary tumor virus-like sequences in human...

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C07K 14/15 (2006.01) C07K 16/10 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2236837

The present invention relates to materials and methods for diagnosing breast cancer in humans. It is based, at least in part, on the discovery that a substantial percentage of human breast cancer tissue samples contained nucleic acid sequences corresponding to a portion of the mouse mammary tumor virus env gene. In contrast, such sequences were absent in almost all other human tissues tested.

Matériaux et procédés permettant de diagnostiquer le cancer du sein chez les humains. La présente invention est fondée en partie sur la découverte selon laquelle un pourcentage considérable d'échantillons de tissus cancéreux mammaires humains contiennent des séquences d'acides nucléiques correspondant à une partie du gène <u>env</u> de virus de tumeur mammaire chez la souris. En contraste, ces séquences sont absentes dans la plupart des autres tissus humains analysés.

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