Detection of microsatellite instability and its use in...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2422310

Methods and kits are disclosed for use in the analysis of microsatellite instability in genomic DNA. Methods and kits are also disclosed which can be used to detect microsatellite instability DNA present in biological materials, such as tumors. The methods and kits of the present invention can be used to detect or diagnose diseases associated with microsatellite instability, such as certain types of cancer.

L'invention concerne des procédés et des matériels pouvant être utilisés dans l'analyse de l'instabilité des microsatellites dans l'ADN génomique. L'invention concerne également des procédés et des matériels pouvant être utilisés pour détecter l'instabilité des microsatellites dans l'ADN présent dans des matières biologiques, tel que des tumeurs. Les procédés et trousses de la présente invention peuvent être utilisés pour détecter ou diagnostiquer des maladies associées à l'instabilité des microsatellites, telles que certains types de cancers.

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