C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2740230
The present inventions relates to methods for detecting NPM1 nucleic acid in acellular body fluid samples and determining whether the nucleic acid contains one or more mutations including insertions and deletions. The methods are useful for predicting prognosis of AML patients that have cells with mutations in the NPM1 gene.
La présente invention concerne des procédés destinés à détecter de lacide nucléique NPMl dans des échantillons de fluide corporel acellulaire et à déterminer si l'acide nucléique contient une ou plusieurs mutations, notamment des insertions et des délétions. Ces procédés sont utiles pour établir un diagnostic prévisionnel de patients atteints d'AML ayant des cellules présentant des mutations sur le gène NPMl.
Borden Ladner Gervais Llp
Quest Diagnostics Investments Incorporated
LandOfFree
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