Detection of physiologically acceptable polymer molecules...

G - Physics – 01 – N

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G01N 33/86 (2006.01) G01N 21/00 (2006.01) G01N 33/487 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2746125

The present invention relates, in general, to methods for detecting the amount of a polymer on a protein using nearinfrared spectroscopy. Measurement of the number of polymer moieties per protein molecule allows for production of molecules having a uniform number of polymer moieties, which is useful in the production of pharmaceutical compositions.

La présente invention concerne, d'une manière générale, des procédés permettant de détecter la quantité d'un polymère sur une protéine au moyen de la spectroscopie proche infrarouge. La mesure du nombre de fractions de polymères par molécule de protéine permet la production de molécules possédant un nombre uniforme de fractions de polymère, ce qui est utile dans la production de compositions pharmaceutiques.

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