C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/04 (2006.01)
Patent
CA 2075053
2075053 9112343 PCTABS00006 The present invention provides a method for detecting whether a point mutation is present in a nucleic acid encoding a GTP bindingprotein or protein subunit. Methods are also provided for characterizing point mutations, if present. In a preferred embodiment, the method involves amplification of a nucleic acid segment followed by sequence-specific probe hybridization. The method is preferred for nucleic acids which encode a G-protein .alpha. subunit or p21 ras protein.
Lyons John F.
Mccormick Francis P.
Gowling Lafleur Henderson Llp
Hoffmann-La Roche (f.) Ag
Lyons John F.
Mccormick Francis P.
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