Detection of reverse transcriptase by dna hybridization assay

Details Detection of reverse transcriptase by dna hybridization assay Detection of reverse transcriptase by dna hybridization assay

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12Q 1/48 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2128235

2128235 9314221 PCTABS00024 A method for detecting reverse transcriptase (RT), utilizing RT-catalyzed generation of cDNA complementary to an RNA template and detecting cDNA in a DNA hybridization reaction, is provided. Also provided is a method for detecting an/or quantitating drug resistance of reverse transcriptase in a sample and a method for evaluating ability of a compound to inhibit reverse transcriptase activity.

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