Detection of small nucleic acids

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2510381

The present invention relates to compositions and methods for the detection and characterization of interfering RNAs such as micro RNAs (miRNAs) and small interfering RNAs (siRNAs) and other short nucleic acid molecules. More particularly, the present invention relates to improved methods for the detection and quantitation of interfering RNA expression. The present invention further provides for the detection of variants and types of miRNAs and siRNAs.

La présente invention concerne des compositions et des méthodes destinées à la détection et à la caractérisation d'ARN interférant, tels que des microARN (miARN) et de petits ARN interférant (siARN) et d'autres molécules d'acides nucléiques courtes. Plus spécifiquement, cette invention a trait à des méthodes améliorées de détection et de quantification de l'expression d'ARN interférant, ainsi qu'à la détection de variants et de types de miARN et siARN.

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