Detection of transmembrane potentials by optical methods

Details Detection of transmembrane potentials by optical methods Detection of transmembrane potentials by optical methods

C - Chemistry, Metallurgy

09

B

C09B 23/12 (2006.01) C07D 209/30 (2006.01) C07D 239/32 (2006.01) C09B 23/00 (2006.01) C09B 55/00 (2006.01) C09B 57/02 (2006.01) G01N 33/50 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2458360

Methods and compositions are provided for determining the potential of a membrane. The present invention also provides fluorescent complexes of lanthanides having the following formulae: (see formula I) (see formula II) These complexes are used in compositions and optical methods for determining transmembrane potentials across the plasma membrane of biological cells.

Des méthodes et des composés sont fournis pour déterminer le potentiel d'une membrane. Cette invention fournit aussi des complexes de lanthanides fluorescents, dont les formules sont les suivantes : (voir formules I et II). Ces complexes sont utilisés dans des composés et dans des méthodes optiques pour déterminer les potentiels transmembranaires de part et d'autre des membranes à plasma des cellules biologiques.

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