Detergent-facilitated immunoassay of pharmacological agents

Details Detergent-facilitated immunoassay of pharmacological agents Detergent-facilitated immunoassay of pharmacological agents

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2196204

Methods for modulating the rates and dose responses of immunoassays through the incorporation of one or more detergents into the immunoassay reaction are disclosed. The methods are particularly suitable for automated immunoassay formats, especially with formats that use analyte-biotin bidentate reagents. The methods may be used to facilitate the detection of any desired, preselected pharmacological agent.

La présente invention concerne des procédés de modulation des taux et réponses aux doses des dosages immunologiques grâce à l'incorporation d'un ou plusieurs détergents dans la réaction de dosage immunologique. Les procédés conviennent particulièrement aux formats de dosages immunologiques automatisés, et notamment aux formats utilisant des réactifs bidentés analysat/biotine. Le procédé peut s'utiliser pour faciliter la détection de n'importe quel agent pharmacologique présélectionné.

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