Determination of foetal lung maturity

Details Determination of foetal lung maturity Determination of foetal lung maturity

G - Physics

01

N

150/14

G01N 33/48 (2006.01) G01N 33/92 (2006.01)

Patent

CA 1119925

DETERMINATION OF FOETAL LUNG MATURITY . ABSTRACT OF THE DISCLOSURE A method of determining foetal lung maturity by reference to the lamiliar body-derived phospholipid level in amniotic fluid surrounding a foetus. A sample of the amniotic fluid is subjected to centrifugation over a cushion material, and lamellar body material which forms a band at the interface between the cushion material and the amniotic fluid during centrifugation is isolated and analysed to determine its phospholipid level. A phospholipid level which is determined to be greater than about 3.5 to 5.0 mg/dl of amniotic fluid indicates a mature foetal lung. -1-

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