Determination of hemodynamic parameters

A - Human Necessities – 61 – B

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A61B 5/00 (2006.01) A61B 6/03 (2006.01) G06F 17/10 (2006.01)

Patent

CA 2577719

Hemodynamic parameters of an organ are determined by first estimating hemodynamic parameters for portions of an organ from time sequenced images of the portions obtained after injection of a contrast agent. For each of the portions, the accuracy of the estimated hemodynamic parameters is assessed based on at least one of (i) a relationship between extraction efficiency product (FE) and contrast distribution volume in interstitial space (Ve); (ii) a relationship between blood plasma space volume (Vp), FE, and Ve; and (iii) a value of contrast distribution volume (VD).

L'invention concerne les paramètres hémodynamiques d'un organe, qui sont déterminés dans un premier temps par l'estimation de paramètres hémodynamiques pour les parties d'un organe provenant de plusieurs images séquencées dans le temps des parties, obtenues après l'injection d'un agent de contraste. Pour chacune des parties, la précision des paramètres hémodynamiques estimés est évaluée sur la base d'au moins ce qui suit: (i) une relation entre le produit d'efficacité d'extraction (FE) et un volume de distribution de contraste dans l'espace interstitiel (Ve); (ii) une relation entre le volume de l'espace de plasma sanguin (Vp), FE et Ve; et (iii) une valeur de volume de distribution de contraste ((V<SB>D</SB>).

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