Determination of triglycerides

Details Determination of triglycerides Determination of triglycerides

C - Chemistry, Metallurgy

07

D

150/11, 260/294.

C07D 211/32 (2006.01) G01N 33/92 (2006.01)

Patent

CA 1101427

ABSTRACT OF THE DISCLOSURE Disclosed is a technique for accelerating the Hantzsch reaction, for the clinical determination of triglyceride, so as to permit the reaction to be analytically complete within 15 minutes at 37° C. As is known, in this Hantzsch reaction, one mole of aldehyde is reacted in a solution predominantly containing alcohol and water with two moles of a beta- dicarbonyl compound in the presence of ammonia to yield, as a colored derivative, a lutidine. In the disclosed technique, the solution also contains an organic accelerator compound. This compound is capable of forming a clear solution with the mixture of components of the reaction solution and is further characterized as having an aprotic internal dipole such that said compound has a distinct center which is electron rich and center which is electron deficient.

291158

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