Determining age ranges of skin samples

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 8/00 (2006.01) C40B 30/04 (2006.01) C40B 40/06 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2734521

The present invention provides methods for characterizing a skin sample of a subject as belonging to an age range by analyzing nucleic acid or protein molecules obtained from the subject. The methods include analyzing expression or mutations in epidermal samples, of one or more skin markers. The methods can include the use of a microarray to analyze gene or protein profiles from a sample and compare them with a known skin age index. Therapeutic and cosmetic formulations are also provided herein.

La présente invention concerne des procédés permettant de caractériser la tranche dâge dun échantillon cutané dun sujet par lanalyse des molécules dacide nucléique ou de protéine obtenues du sujet. Les procédés consistent à analyser lexpression ou les mutations dans les échantillons dépiderme, dun marqueur cutané ou plus. Les procédés peuvent consister à utiliser une micropuce pour analyser les profils des gènes ou des protéines à partir dun échantillon et à les comparer avec un répertoire dâges cutanés connu. Linvention concerne également des préparations thérapeutiques et cosmétiques.

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