Deuterated catecholamine derivatives and medicaments...

C - Chemistry – Metallurgy – 07 – B

Patent

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Details

C07B 59/00 (2006.01) A61K 31/198 (2006.01) A61P 25/00 (2006.01) C07C 229/08 (2006.01)

Patent

CA 2513088

The invention relates to deuterated catecholamine derivatives and medicaments comprising said compounds. The invention further relates to the use of deuterated catecholamine derivatives, the pharmacologically-acceptable salts thereof and pharmaceutical compositions containing said compounds, also in combination with enzyme inhibitors, for the treatment of dopamine deficiency diseases or diseases relating to disturbed tyrosine transport or disturbed tyrosine decarboxylase and other diseases.

La présente invention concerne des dérivés de catécholamines deutérés et l'utilisation desdits dérivés et de leurs sels physiologiquement acceptables, ainsi que des compositions pharmaceutiques contenant ces composés, également en combinaison avec des inhibiteurs d'enzymes, pour le traitement de maladies dues à une carence en dopamine et de maladies provoquées par une perturbation du transport de la tyrosine ou une perturbation de la tyrosine décarboxylase, ainsi que d'autres maladies.

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