Deuterated inhibitors of gastric h+, k+-atpase with enhanced...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 1/00 (2006.01)

Patent

CA 2624179

Chemical syntheses and medical uses of deuterated inhibitors of formula I of the gastric H+ , K+ -ATPase for the treatment and/or management of duodenal ulcers, heartburn, acid reflux, other conditions mediated by gastric acid secretion and/or psoriasis are described.

L'invention concerne les synthèses chimiques et des utilisations médicales d'inhibiteurs deutériés selon la formule I de l'ATPase H+, K+gastrique pour le traitement et/ou la gestion d'ulcères du duodénum, de brûlures d'estomac, de reflux acide ou d'autres états liés à des sécrétions gastriques acides et/ou à un psoriasis.

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