Deuterated n-substituted and .alpha.-substituted...

C - Chemistry – Metallurgy – 07 – B

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C07B 59/00 (2006.01) A61K 31/445 (2006.01) A61P 13/10 (2006.01) C07D 211/46 (2006.01)

Patent

CA 2451638

The invention relates to deuterated N-substituted .alpha.,.alpha.-diphenyl- .alpha.-alkoxy acetic acid amino alkyl esters and to their physiologically compatible salts. The invention also relates to the use of deuterated N- substituted .alpha.,.alpha.-diphenyl-.alpha.-alkoxy acetic acid amino alkyl esters for treating hypertonic functional states in the area of the urinary bladder and for producing medicaments used in the treatment of hypertonic functional states in the area of the urinary bladder. The invention additionally relates to pharmaceutical preparations containing N-substituted .alpha.,.alpha.-diphenyl-.alpha.-alkoxy acetic acid amino alkyl esters and to the physiologically compatible salts thereof for treating hypertonic functional states in the area of the urinary bladder in addition to pharmaceutically compatible adjuvants and/or additives.

L'invention concerne des aminoalkylesters d'acide .alpha.,.alpha.-diphényl-.alpha.-alcoxy-acétique N-substitués deutérisés, ainsi que leurs sels physiologiquement compatibles. L'invention concerne en outre l'utilisation d'aminoalkylesters d'acide .alpha.,.alpha.-diphényl-.alpha.-alcoxy-acétique N-substitués deutérisés, pour traiter des états fonctionnels d'hypertonie dans la zone de la vessie, ainsi que la production de médicaments pour traiter des états fonctionnels d'hypertonie dans la région de la vessie, en plus d'auxiliaires et/ou d'additifs pharmaceutiquement compatibles.

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