C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 15/00 (2006.01) C07D 231/00 (2006.01) C07D 239/00 (2006.01)
Patent
CA 2470271
The invention relates to deuterated pyrazolopyrimidinones and drugs containing said compounds and to the use of said pyrazolopyrimidinones for inhibiting thrombocyte adhesion and aggregation, for the purpose of long-term improvement of memory performance and learning ability and for use in the treatment of heart diseases and cardiovascular diseases, hypertension, pulmonary hypertension, erectile dysfunction and obstructive respiratory diseases, such as for example bronchial asthma. The invention further relates to pharmaceutical compositions of deuterated pyrazolopyrimidinones and the physiologically acceptable salts thereof for inhibiting thrombocyte adhesion and aggregation, for the purpose of long-term improvement of memory performance and learning ability and for use in the treatment of heart diseases and cardiovascular diseases, hypertension, pulmonary hypertension, erectile dysfunction and obstructive respiratory diseases, such as for example bronchial asthma, combined with pharmaceutically acceptable adjuvants and/or additives.
L'invention concerne des pyrazolopyrimidinones deutérées, des médicaments contenant ces composés et l'utilisation de pyrazolopyrimidinones deutérées pour inhiber l'adhésion et l'agrégation des thrombocytes, pour améliorer à long terme la mémoire et l'aptitude à apprendre et pour traiter des maladies cardiaques et circulatoires, l'hypertonie, l'hypertonie pulmonaire, la dysfonction érectile et les maladies respiratoires obstructives comme, par ex., l'asthme bronchique. La présente invention porte également sur des préparations pharmaceutiques de pyrazolopyrimidinones deutérées et sur leurs sels physiologiquement acceptables pour inhiber l'adhésion et l'agrégation des thrombocytes, pour améliorer à long terme la mémoire et l'aptitude à apprendre et pour traiter des maladies cardiaques et circulatoires, l'hypertonie, l'hypertonie pulmonaire, la dysfonction érectile et les maladies respiratoires obstructives comme, par ex., l'asthme bronchique, ainsi que sur des auxiliaires et/ou additifs pharmaceutiquement acceptables.
Bdd Berolina Drug Development Gmbh
Macrae & Co.
Turicum Drug Development Ag
LandOfFree
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