Development of a mechanism-based screen to identify androgen...

Details Development of a mechanism-based screen to identify androgen... Development of a mechanism-based screen to identify androgen...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 14/00 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12N 15/12 (2006.01) C12N 15/81 (2006.01) C12Q 1/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2095712

31,724-00 DEVELOPMENT OF A MECHANISM-BASED SCREEN TO IDENTIFY ANDROGEN RECEPTOR AGONISTS AND ANTAGONISTS ABSTRACT OF THE INVENTION The present invention relates to a novel androgen receptor screening method using a yeast-based expression system. The use of this yeast system enhances the ability to screen for agonists and/or antagonists of the steroid thyroid receptor superfamily. Furthermore, the use of this yeast system allows the localization and identification of functional domains of the androgen receptor.

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