G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/543 (2006.01)
Patent
CA 2579414
The invention relates to a device for the analysis of interactions between biomolecules, comprising a support on which a number of biomolecules are immobilised on the surface of the support material in a regular or irregular arrangement, by means of linkers, whereby two biomolecules are bonded to each linker. The invention further relates to a method for detection of interactions between biopolymers immobilised on a surface, comprising the steps of preparation of a device, according to one of the above claims, setting a defined separation between two biopolymers, immobilised on the surface and the measuring of a signal, generated by the interaction between the two biopolymers.
La présente invention concerne un dispositif permettant d'analyser des interactions entre des biomolécules, lequel dispositif comprend un support sur lequel une pluralité de biomolécules sont immobilisées sur la surface du matériau support selon un agencement régulier ou irrégulier au moyen de lieurs, deux biomolécules étant liées à chaque lieur. Cette invention concerne également un procédé pour déceler des interactions entre des biopolymères immobilisés sur une surface, lequel procédé consiste à réaliser un dispositif selon une des revendications formulées, à régler une distance définie entre deux biopolymères immobilisés sur la surface et à mesurer un signal engendré par l'interaction entre ces deux biopolymères.
Fischer Gunter
Malesevic Miroslav
Schiene-Fischer Cordelia
Schutkowski Mike
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.v.
Zsigmond Otto
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