G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 21/03 (2006.01) B01L 3/00 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2565679
The invention relates to devices and methods for detecting specific interactions between probe and target molecules. The invention especially relates to a device for the qualitative and/or quantitative detection of molecular interactions between probe and target molecules, which comprises a) a microarray comprising a substrate on which probe molecules are immobilized on array elements, said microarray being located on a first surface of the device; and b) a reaction chamber that is defined between the first area with the microarray disposed thereon and a second surface, the distance between the microarray and the second surface being modifiable.
L'invention concerne un dispositif et un procédé permettant de détecter des interactions spécifiques entre des molécules sondes et des molécules cibles. L'invention concerne notamment un dispositif de détection qualitative et/ou quantitative d'interactions moléculaires entre des molécules sondes et des molécules cibles. Ledit dispositif comprend: a) un jeu ordonné de microéchantillons comportant un substrat sur lequel des molécules sondes sont immobilisées sur des éléments de jeu ordonné d'échantillons, le jeu ordonné de microéchantillons étant disposé sur une première surface du dispositif; et b) une chambre de réaction formée entre la première surface avec le jeu ordonné de microéchantillons disposé dessus et une seconde surface, l'écart entre le jeu ordonnée de microéchantillons et la seconde surface étant modulable.
Bickel Ralf
Dworrak Alexandra
Ellinger Thomas
Ermantraut Eugen
Kaiser Thomas
Clondiag Chip Technologies Gmbh
Sim & Mcburney
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