A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 31/00 (2006.01) A61K 9/00 (2006.01)
Patent
CA 2635337
A rectally insertable device for localized drug delivery to the anal sphincter of a subject, a method of using the device and the use of the device is disclosed. The device comprises a shell for containing an active pharmaceutical ingredient, the shell being substantially impermeable to the active pharmaceutical ingredient wherein a lower portion of the shell is configured to release the active pharmaceutical ingredient from the shell and wherein when the device is inserted into the rectum of the subject, the lower portion of the shell is proximal to the anal sphincter, such that the active pharmaceutical ingredient is released proximal to the anal sphincter.
La présente invention concerne un dispositif pouvant être inséré par voie rectale destiné à l'administration localisée de médicament au sphincter anal d'un sujet, un procédé d'utilisation du dispositif et l'utilisation du dispositif. Le dispositif comprend une enveloppe contenant un ingrédient pharmaceutique actif, l'enveloppe étant sensiblement imperméable audit ingrédient, une partie inférieure de l'enveloppe étant conçue pour libérer ledit ingrédient de l'enveloppe. Lorsque le dispositif est inséré dans le rectum du sujet, la partie inférieure de l'enveloppe se trouve à proximité du sphincter anal, de telle sorte que ledit ingrédient soit libéré à proximité du sphincter anal.
Integral Ip
Mor - Research Applications Ltd.
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