Device and method for treating weight disorders

A - Human Necessities – 61 – B

Patent

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Details

A61B 10/00 (2006.01) A61H 1/00 (2006.01) A61M 29/00 (2006.01)

Patent

CA 2582929

An apparatus and a method for treating a weight disorder in a subject are provided. The apparatus comprising an implantable device such as an inflatable balloon (12) and electrodes (32) capable of sensing a physiological change associated with good ingestion or hunger and a mechanism adapted for directly stimulating a region such as the duodeum which is responsive to a gastrointestinal satiety agent, such a mechanism can be a drug reservoir containing a drug such as CCK or analogs thereof which is contained within an inflatable balloon being implantable in a stomach of the subject. The apparatus-and method provided here combine synergistic approaches to limiting meal size, i.e.; chemo and mechano receptor activation of vagal satiety stimuli, electric stimulation of specific vagal pathways and limitations of gastric space.

L'invention concerne un appareil et une méthode permettant de traiter un trouble pondéral chez un sujet. Cet appareil comprend un dispositif implantable, tel qu'un ballonnet gonflable et des électrodes permettant de détecter un changement physiologique lié à une ingestion d'aliments ou à la faim, et un mécanisme élaboré pour stimuler directement une région, par exemple, le duodénum qui est sensible à un agent de satiété gastro-intestinal. Ce mécanisme peut être un réservoir à médicaments contenant un médicament, comme CCK ou des analogues associés, qui sont contenus à l'intérieur du ballonnet gonflable implantable dans l'estomac du sujet. Cet appareil et ce procédé permettent de combiner des approches synergiques en vue de limiter la taille du repas, à savoir, l'activation par le chimio- et mécano-récepteur des stimuli de satiété vagale, la stimulation électrique de voies vagales spécifiques et les limitations de l'espace gastrique.

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