A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/38 (2006.01) A61B 1/00 (2006.01) A61F 2/00 (2006.01) A61F 2/01 (2006.01) A61K 9/22 (2006.01) A61L 27/00 (2006.01) A61L 27/14 (2006.01) A61M 1/14 (2006.01) A61M 1/16 (2006.01) A61M 1/34 (2006.01) A61M 1/36 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 11/02 (2006.01) C12N 11/08 (2006.01)
Patent
CA 2459280
A device and a method of maintaining vascularization near an implant, especially a bioartificial hemofilter. By associating cells that excrete angiogenic factors with such an implant, vascularization to the tissue surrounding the implant can be maintained. In a bioartificial hemofilter, this facilitates filtrate transport to a collection fiber for drainage from the body. The cells can be generically engineered, for example using an adenovirus vector encoding for vascular endothelial growth factor. Myoblasts and myotubes may be used in one embodiment of the present invention.
Dispositif et procédé servant à maintenir une vascularisation à proximité d'un implant, notamment d'un hémofiltre artificiel biologique. En associant à l'implant des cellules excrétant des facteurs angiogéniques, on maintient une vascularisation vers le tissu entourant l'implant. Dans un hémofiltre artificiel biologique, l'invention facilite le transport de filtrat vers une fibre collectrice à des fins de drainage. Lesdites cellules peuvent être mises au point génétiquement, par exemple à l'aide d'un vecteur adénoviral codant pour un facteur de croissance endothéliale vasculaire. Des myoblastes et des myotubes peuvent être utilisés dans une forme de réalisation de l'invention.
Buffington Deborah A.
Fissell William H.
Humes H. David
Tziampazis Evangelos
Nephros Therapeutics
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Regents Of The University Of Michigan
LandOfFree
Device and method to maintain vascularization near implant does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Device and method to maintain vascularization near implant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Device and method to maintain vascularization near implant will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1918781