Device and process for measuring cell properties

G - Physics – 01 – N

Patent

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G01N 33/487 (2006.01) G01N 27/30 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2585763

The invention relates to a measuring device for measuring at least one property of cells or vesicles, characterized in that is divided into two chambers by a hydrophobic partition having a horizontal opening, these chambers containing electrolyte solution and said opening being closed by a lipid double layer. The invention is characterized in that at least one cell or vesicle contacts the lipid double layer. The invention also relates to methods involving the use of the measuring device and to arrays, measuring chambers and microtitration plates all suited therefor.

L'invention concerne un dispositif de mesure permettant de détecter une propriété de cellules ou de vésicules, qui divisé en deux chambres, par une cloison de séparation hydrophobe, présentant une ouverture horizontale, ladite ouverture étant fermée par une membrane à double couche lipidique. Ledit dispositif de mesure se caractérise en ce qu'au moins une cellule ou vésicule est au contact de la membrane à double couche lipidique. L'invention concerne en outre des procédés faisant appel audit dispositif de mesure et des jeux ordonnés d'échantillons, des chambres de mesure et des plaques de microtitration appropriés.

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