G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 21/21 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)
Patent
CA 2639248
The invention relates to a device for determining the concentration of a substance present in a solution, using ellipsometry. Said device is used for determining the rate of precipitation, which is a measure of the concentration of the substance to be determined. The object of the invention is to provide an improved measuring technique based on optical ellipsometry or another technique for measuring the mass bonded to a solid surface (substrate), such as "surface plasmon resonance" (SPR), "quartz crystal microbalance" (QCM) etc, by means of which the concentration of a substance present in a liquid, which liquid is in contact with the substrate, can be measured with a higher degree of accuracy. According to the invention, the device is to that end characterised in that said substance is glucose, wherein the substrate comprises glucose oxidase (GOX) and/or horseradish peroxidase (HRP) bonded thereto, and wherein said means are arranged for determining the presence of glucose on the basis of the precipitation rate of diaminobenzene (DAB) on the substrate as measured during operation.
Delbia B.v.
Sim & Mcburney
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