Device for in situ production and topical administration of...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/70 (2006.01) A61K 31/255 (2006.01) A61K 36/8962 (2006.01)

Patent

CA 2720030

The present invention relates to a drug delivery device that is useful for topical treatment of various infections such as skin and nail, or vaginal infections. More specifically, the invention provides a device for topical administration of allicin to an infection site, comprising either one solid carrier or two adjacent solid carriers, dry alliin and dry alliinase, wherein either a mix-ture of said dry alliin and dry alliinase is contained within said one solid carrier or dry alliin and dry alliinase are each separately contained within each one of said two adjacent solid carriers, whereby in contact with the infection site and a wetting agent, the al-iinase acts on the alliin and allicin is produced in situ and administered to the infection site

La présente invention porte sur un dispositif d'administration de médicament qui est utile pour un traitement topique de diverses infections telles que des infections de la peau et des ongles, ou des infections vaginales. Plus spécifiquement, l'invention porte sur un dispositif pour une administration topique d'allicine à un site d'infection, comprenant soit un support solide, soit deux supports solides adjacents, de l'alliine sèche et de l'alliinase sèche, dans lequel soit un mélange de ladite alliine sèche et de ladite alliinase sèche est contenu dans ledit support solide, soit de l'alliine sèche et de l'alliinase sèche sont chacune contenues séparément dans chacun desdits deux supports solides adjacents, ce par quoi, en contact avec le site d'infection et un agent mouillant, l'alliinase agit sur l'alliinine et de l'allicine est produite in situ et administrée au site d'infection.

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