Device for ligand receptor methods

Details Device for ligand receptor methods Device for ligand receptor methods

G - Physics

01

N

167/44

G01N 33/544 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/558 (2006.01) G01N 37/00 (2006.01)

Patent

CA 2037963

Devices for use in either competitive or noncompetitive ligand-receptor assays, having a microporous member in contact with a non-absorbent textured surface, where the surface texturing is such that a capillary network is formed when in contact with the microporous member. More particularly, these devices comprise: a porous member having an upper and a lower surface, said sample being applied to said upper surface; and a non-absorbent member having a textured surface with channels capable of forming a network of capillary channels when placed in communication beneath or around said porous member, said capillary network substantially parallel to the lower surface of said porous member; whereby sample, alone or in combination with other fluids is drawn through said porous member to said capillary network formed between said porous member and said non-absorbent member when substantially all the void volume of said porous member is filled with said sample and/or fluids and when contact is made between said porous member and said non-absorbent member. These devices are suitable for use in ligand-receptor assays (also claimed) which axe performed using either immunochromatographic methods or in those which are performed using flow-through methods.

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