G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/49 (2006.01) A61B 5/00 (2006.01) A61B 10/00 (2006.01) G01N 27/02 (2006.01) G01N 27/22 (2006.01)
Patent
CA 2432535
A device and method for measuring the clotting times in a fluid, typically blood, within a microchannel whereby the onset of clotting is determined by measurement of the rate of change or value of capacitance or impedance between two electrodes situated on either side of the microchannel. There is provided a disposable test-strip (100) comprising an upper and lower support (101) and (103). A microchannel (102) is formed into the upper surface of the lower support member (103). A second substrate layer (101) is laminated on top of the support member (103), thereby closing the open microchannel (102). Electrodes (104) are formed on the respective outer surfaces of the substrate layers and coplanar to the channel.
L'invention concerne un dispositif et un procédé destinés à mesurer les temps de coagulation dans un fluide, typiquement du sang, à l'intérieur d'un microcanal, le début de la coagulation étant déterminé par mesure de la vitesse de changement ou de la valeur de la capacité ou de l'impédance entre deux électrodes disposées de chaque côté du microcanal. On met en oeuvre une bandelette test jetable (100) comprenant un support supérieur (101) et un support inférieur (103). On forme un microcanal (102) dans la surface supérieure de l'élément support inférieur (103). Une seconde couche de substrat (101) est stratifiée sur le dessus de l'élément support (103), ce qui permet de fermer le microcanal ouvert (102). Des électrodes (104) sont formées sur les surfaces extérieures respectives des couches de substrat, coplanaires par rapport au canal.
Allen John
Alvarez-Icaza Manuel
Mcaleer Jerome
Plotkin Elliot
Richter Tanja
Inverness Medical Limited
Lifescan Scotland Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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