Device for taking up and transferring biological samples

C - Chemistry – Metallurgy – 12 – M

Patent

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Details

C12M 1/32 (2006.01) B01L 3/00 (2006.01)

Patent

CA 2296025

The invention relates to a device (2) for the targeted uptake of biological samples (e.g. 46, 48) and the transfer thereof into predetermined compartments (50) of a microtitration plate (52) by means of a corresponding number of needle-shaped sample uptake elements (14) which can be moved in a controlled manner. The inventive device is characterized in that the sample uptake elements are part of a flexible band (4) which can be progressively advanced and extracted by means of a switching and guiding device (6) which can be hand held. Said elements are arranged in said band such that they are perpendicular to the direction of advancement and such that they are adjacent in a manner similar to the teeth of a comb. In addition, the elements are arranged at distances which correspond to the distances of the compartments (50) of each row of the utilized microtitration plates (52). The inventive device is also characterized in that the switching and guiding devices (6) can divert the band (4) in such a way that, in each step switching position of the band, each one of the sample uptake elements projects outward with the tip thereof from the row of the remaining sample uptake elements. By using the device (2), the individual sample uptake elements (14) can be individually loaded in a successive manner with the samples to be taken up. Said band (4) is withdrawn from the switching and guiding device (6) and is dipped into a row of compartments (50) of the microtitration plate (52) in extended form with the sample uptake elements (14) thereof.

L'invention concerne un appareil (2) pour collecter de manière ciblée des échantillons biologiques (par ex. 46, 48) et les transférer dans des compartiments (50) prédéterminés d'une plaque de microtitration (52) à l'aide d'un nombre correspondant d'éléments de collecte d'échantillons (14) sous forme d'aiguilles, déplaçables de manière commandée. Cet appareil se caractérise en ce que les éléments de collecte d'échantillons font partie d'une bande (4) souple pouvant être avancée progressivement à l'aide d'un dispositif de commutation et de guidage (6) portatif et en être ressortie. Ces éléments sont disposés transversalement au sens d'avancement, à la manière des dents d'un peigne, les uns à côté des autres, à des intervalles correspondant aux écarts entre les compartiments (50) de chaque rangée des plaques de microtitration (52) utilisées. Le dispositif de commutation et de guidage (6) peut renvoyer la bande (4) de manière que dans chaque position de commutation par pas de la bande, un élément de collecte d'échantillons fasse dans chaque cas saillie vers l'extérieur avec sa pointe hors de la rangée des autres éléments de collecte d'échantillon. Les éléments de collecte d'échantillons (14) individuels peuvent ainsi être chargés en échantillons voulus les uns à la suite des autres à l'aide dudit appareil (2). La bande (4) concernée peut ensuite être enlevée du dispositif de commutation et de guidage (6) et être plongée sous forme étirée conjointement avec ses éléments de collecte d'échantillons (14) dans une rangée de compartiments (50) de la plaque de microtitration (52).

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