Device for treating back pain by re-establishing the...

Details Device for treating back pain by re-establishing the... Device for treating back pain by re-establishing the...

A - Human Necessities

61

B

A61B 17/88 (2006.01)

Patent

CA 2524443

The intervertebral disc is avascular. With aging, endplates become occluded by calcified layers, and diffusion of nutrients and oxygen into the disc diminishes. The disc degenerates, and pain ensues. Conduits are delivered and deployed into the intervertebral disc to reestablish the exchange of nutrients and waste between the disc and bodily circulation to stop or reverse disc degeneration and relieve pain. The intervertebral disc installed with semi- permeable conduits may be used as an immuno-isolated capsule to encapsulate donor cells capable of biosynthesizing therapeutic molecules. The semi- permeable conduits establish the exchange of nutrients and therapeutic molecules between disc and bodily circulation to treat a disease without using immunosuppressive drugs.

Le disque intervertébral est avasculaire. Avec l'âge, les plateaux vertébraux se recouvrent de couches calcifiées et la diffusion d'éléments nutritifs et d'oxygène dans le disque diminue. Le disque dégénère, ce qui provoque la douleur. Afin de stopper ou d'inverser la dégénérescence du disque et de soulager la douleur, des conduits sont amenés et déployés dans le disque intervertébral afin de rétablir l'échange d'éléments nutritifs et de déchets entre le disque et la circulation corporelle. Le disque intervertébral installé avec des conduits semi-perméables peut être utilisé comme une capsule immuno-isolée afin d'encapsuler les cellules donatrices capables de biosynthétiser les molécules thérapeutiques. Les conduits semi-perméables établissent l'échange d'éléments nutritifs et de molécules thérapeutiques entre le disque et la circulation corporelle afin de traiter une maladie, sans faire appel à des médicaments immunodépresseurs.

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