Device with an expandable portion for drug release

A - Human Necessities – 61 – M

Patent

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Details

A61M 31/00 (2006.01)

Patent

CA 2500928

The present invention relates to a medical device and a method of delivering a drug to a target circulation or tissue. The medical device has an expandable portion (16) which is fabricated from a porous elastomeric material with a plurality of voids (18)therein. The voids (18) are loaded with drugs (22) in various formulations. Upon inflation of the expandable portion (16), the overall diameter (26) increases, the wall (19) thickness (28) decreases and, consequently, the voids (18) are stretched to cause the drug to be expelled from the voids (18) and into the bodily lumen or tissue adjacent to the medical device. The voids (18) include any open volume within the expandable portion (16) capable of containing the drug (22).

La présente invention concerne un dispositif médical et un procédé de délivrance d'un médicament à une circulation ou un tissu cible. Ce dispositif médical a une parte extensible (16) qui est réalisée dans un matériau élastomère poreux doté d'une pluralité de cavités (18). Les cavités (18) sont chargées de médicaments (22) de diverses formulations. Lors du gonflement de la partie extensible (16), le diamètre total (26) augmente, l'épaisseur (28) de la paroi (19) décroît et, par conséquent, les cavités (18) sont étirées pour provoquer l'expulsion du médicament des cavités (18) et son introduction dans le lumen ou tissu de l'organisme adjacent au dispositif médical. Les cavités (18) incluent tout volume ouvert dans la partie extensible (16) pouvant contenir le médicament (22).

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