A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 35/00 (2006.01) A61B 17/03 (2006.01) A61L 24/10 (2006.01) A61M 31/00 (2006.01)
Patent
CA 2583144
Novel methods and devices which provide enhanced mixing, and application of two liquid components to form a biomaterial with minimized aerosols, are achieved using airflow rates below about 1.25 liters/minute in combination with a ratio of airflow to total liquid flow of from about 150:1 up to about 1500:1. Preferably the airflow is below about 1 liter/minute, and the ratio of airflow to total liquid flow is from about 200:1 to about 1200:1. The parameters are ideally suited for the spray application of components which form a surgical sealant, e.g., a fibrin sealant. Also a part of the present invention is novel application methods for biomaterial, e.g., surgical sealant, components at liquid flows below 1.9 ml/minute, novel methods involving the mixing of such components on the exit surface of a spray tip (14), or nozzle, novel spray tips (14), biomaterial applicators, and methods for making such applicators.
Cornwell Richard
Holm Niels Erik
Linnebjerg Steven
Bristol Myers Squibb Company
Osler Hoskin & Harcourt Llp
Vivolution A/s
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